Rosterolon

17α-propylmesterolone veya 1α-methyl-17α-propyl-5α-androstan-17β-ol-3-one olarak da bilinen Rosterolon (gelişimsel kod adı SH-434), ilk kez 1984'te tanımlanan bir steroidal antiandrojendir. Topikal uygulama için geliştirilmiş, ancak asla pazarlanmamıştır.^[1]^[2] Akne tedavisinde bir miktar etkinlik göstermiştir ve topikal veya sistemik uygulamada sistemik etkilerden yoksundur.^[1]^[2]^[3] Rosterolon, bir androjen ve anabolik steroid olan mesterolonun bir türevidir.

Kaynakça[değiştir | kaynağı değiştir]

^ ^a ^b "17 alpha-Propylmesterolone (SH 434): an antiandrogenic sebosuppressive substance not influencing circulating testosterone concentrations. Experimental studies in Syrian hamsters". Naunyn-Schmiedeberg's Archives of Pharmacology. 328 (2): 214-8. December 1984. doi:10.1007/BF00512076. PMID 6527707.
^ ^a ^b "Androgen receptor antagonists (antiandrogens): structure-activity relationships". Current Medicinal Chemistry. 7 (2): 211-47. February 2000. doi:10.2174/0929867003375371. PMID 10637363.
^ "Antiandrogens and Hair Growth: Basic Concepts and Experimental Research". Hair and Hair Diseases. 1990. ss. 791-826. doi:10.1007/978-3-642-74612-3_34. ISBN 978-3-642-74614-7.

[LuderschmidtEiermann1984-1] "17 alpha-Propylmesterolone (SH 434): an antiandrogenic sebosuppressive substance not influencing circulating testosterone concentrations. Experimental studies in Syrian hamsters". Naunyn-Schmiedeberg's Archives of Pharmacology. 328 (2): 214-8. December 1984. doi:10.1007/BF00512076. PMID 6527707.

[SinghGauthier2000-2] "Androgen receptor antagonists (antiandrogens): structure-activity relationships". Current Medicinal Chemistry. 7 (2): 211-47. February 2000. doi:10.2174/0929867003375371. PMID 10637363.

[NeumannTöpert1990-3] "Antiandrogens and Hair Growth: Basic Concepts and Experimental Research". Hair and Hair Diseases. 1990. ss. 791-826. doi:10.1007/978-3-642-74612-3_34. ISBN 978-3-642-74614-7.

[1]

[2]

[3]