Tiratrikol: Revizyonlar arasındaki fark
StormBlade (mesaj | katkılar) Yeni sayfa: {{drugbox | IUPAC_name = 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]<br>acetic acid | image = Tiratricol.svg | CAS_number = 51-24-1 | ATC_prefix = H... |
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Sayfanın 07.14, 26 Ağustos 2008 tarihindeki hâli
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| Klinik verisi | |
|---|---|
| Diğer adlar | 3,3',5-triiodothyroacetic acid TRIAC |
| ATC kodu | |
| Farmakokinetik veri | |
| Protein bağlanma | Presumed high |
| Metabolizma | Hepatic glucuronidation |
| Boşaltım | Biliary |
| Tanımlayıcılar | |
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| CAS Numarası | |
| PubChem CID | |
| CompTox Bilgi Paneli (EPA) | |
| ECHA Bilgi Kartı | 100.000.079 |
| Kimyasal ve fiziksel veriler | |
| Formül | C14H9I3O4 |
| Mol kütlesi | 621.932 g/mol g·mol−1 |
Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. It is indicated in the management of thyroid hormone resistance syndrome[1] and is used, in combination with levothyroxine, to suppress thyroid-stimulating hormone production in patients with thyroid cancer.
Tiratricol has also been widely marketed, under various trade names, as a weight loss aid. In 1999 and 2000, the United States Food and Drug Administration and Health Canada both issued warnings to the public regarding the use of dietary supplements containing tiratricol.[2][3]
Legal status
Tiratricol is not approved for sale in Canada or the United States. It was once an approved drug in Brazil, but its marketing authorization was suspended in 2003, effectively prohibiting its sale.[4]
Kaynaklar
- ^ Carvalho GA, Ramos HE (2004). "[Thyroid hormone resistance syndrome]". Arq Bras Endocrinol Metabol (Portuguese). 48 (1): 83–92. doi:/S0004-27302004000100010
|doi=değerini kontrol edin (yardım). PMID 15611821. Şablon:PDFlink - ^ "FDA Warns Against Consuming Dietary Supplements Containing Tiratricol" (Basın açıklaması). U.S. Food and Drug Administration. November 21 2000. Erişim tarihi: 2007-08-08. Tarih değerini gözden geçirin:
|date=(yardım) - ^ "Health Canada issues warning on products containing Tiratricol (TRIAC)" (Basın açıklaması). Health Canada. December 2 1999. Erişim tarihi: 2007-08-08. Tarih değerini gözden geçirin:
|date=(yardım) - ^ "Anvisa suspende Tiratricol" (Portuguese). Brazilian Society of Endocrinology and Metabolism. Erişim tarihi: 2007-08-08.