Meprylcaine: Revizyonlar arasındaki fark

İçerik silindi İçerik eklendi

Satır içi

Sayfanın 12.48, 15 Kasım 2021 tarihindeki hâli

Meprylcaine (Epirocaine ve Oracaine olarak da bilinir) , yapısal olarak dimetokain ile ilişkili uyarıcı özelliklere sahip lokal bir anesteziktir.^[1]

Meprylcaine, monoamin taşıyıcı üzerinde nispeten güçlü bir inhibitör etkiye sahiptir ve dopamin, norepinefrin ve serotoninin geri alımını engeller.^[2]^[3]

Kaynakça

^ "Selective inhibition of monoamine neurotransmitter transporters by synthetic local anesthetics". Naunyn-Schmiedeberg's Archives of Pharmacology. 361 (2): 214–20. February 2000. doi:10.1007/s002109900184. PMID 10685879.
^ "Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics". Brain Research. 964 (1): 83–90. February 2003. doi:10.1016/S0006-8993(02)04068-4. PMID 12573515.
^ "Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities" (PDF). Brain Research. 1057 (1–2): 153–60. September 2005. doi:10.1016/j.brainres.2005.07.049. PMID 16125150. KB1 bakım: göster-yazarlar (link)

[1] "Selective inhibition of monoamine neurotransmitter transporters by synthetic local anesthetics". Naunyn-Schmiedeberg's Archives of Pharmacology. 361 (2): 214–20. February 2000. doi:10.1007/s002109900184. PMID 10685879.

[2] "Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics". Brain Research. 964 (1): 83–90. February 2003. doi:10.1016/S0006-8993(02)04068-4. PMID 12573515.

[3] "Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities" (PDF). Brain Research. 1057 (1–2): 153–60. September 2005. doi:10.1016/j.brainres.2005.07.049. PMID 16125150. KB1 bakım: göster-yazarlar (link)

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