Frederick Sanger: Revizyonlar arasındaki fark

Vikipedi, özgür ansiklopedi
Etkileşimli olarak geçmişe göz at
[kontrol edilmiş revizyon][kontrol edilmiş revizyon]
← Önceki sürümle aradaki farkSonraki sürümle aradaki fark →
İçerik silindi İçerik eklendi
GörselVikimetin
Drgulcu (mesaj | katkılar)
Devriyeler
27.877 değişiklik
Değişiklik özeti yok
Drgulcu (mesaj | katkılar)
Devriyeler
27.877 değişiklik
Değişiklik özeti yok
29. satır: 29. satır:


Sanger iki [[Nobel Ödülü]]'ne layık görülen dört kişiden birisidir.
Sanger iki [[Nobel Ödülü]]'ne layık görülen dört kişiden birisidir.

==Seçilmiş yayınları==
<div class='references-small'>
*{{citation | last1= Sanger | first1=F. | last2=Tuppy | first2=H. | year=1951a | title= The amino-acid sequence in the phenylalanyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates | journal=Biochemical Journal | volume=49 | issue= 4 | pages=463–481 | pmid=14886310 | pmc=1197535 }}.
*{{citation | last1= Sanger | first1=F. | last2=Tuppy | first2=H. | year=1951b | title= The amino-acid sequence in the phenylalanyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates | journal=Biochemical Journal | volume=49 | issue= 4 | pages=481–490 | pmid=14886311 | pmc=1197536 }}.
*{{citation | last1= Sanger | first1=F. | last2= Thompson | first2=E.O.P. | year=1953a | title= The amino-acid sequence in the glycyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates | journal=Biochemical Journal | volume=53 | issue= 3 | pages=353–366 | pmid=13032078 | pmc=1198157 }}.
*{{citation | last1= Sanger | first1=F. | last2= Thompson | first2=E.O.P. | year=1953b | title= The amino-acid sequence in the glycyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates | journal=Biochemical Journal | volume=53 | issue= 3 | pages=366–374 | pmid=13032079 | pmc=1198158 }}.
*{{citation | last1=Sanger | first1=F. | last2=Thompson | first2=E.O.p. | last3=Kitai | first3=R. | year=1955 | title=The amide groups of insulin | journal=Biochemical Journal | volume=59 | issue=3 | pages=509–518 | pmid=14363129 | pmc=1216278 }}.
*{{citation | last1=Ryle | first1=A.P. | last2=Sanger | first2=F. | last3=Smith | first3=L.F. | last4=Kitai | first4=R. | year=1955 | title=The disulphide bonds of insulin | journal=Biochemical Journal | volume=60 | issue=4 | pages=541–556 | pmid=13249947 | pmc=1216151 }}.
*{{citation | last1=Brown | first1=H. | last2=Sanger | first2=F. | last3=Kitai | first3=R. | year=1955 | title= The structure of pig and sheep insulins | journal=Biochemical Journal | volume=60 | issue=4 | pages=556–565 | pmid=13249948 | pmc=1216152 }}.
*{{citation | last=Sanger | first=F. | year=1959 | title= Chemistry of Insulin: determination of the structure of insulin opens the way to greater understanding of life processes | journal=Science | volume=129 | pages=1340–1344 | doi=10.1126/science.129.3359.1340 | pmid=13658959 | issue=3359|bibcode = 1959Sci...129.1340G }}.
*{{citation | last1=Milstein | first1=C. | last2= Sanger | first2=F. | year=1961 | title= An amino acid sequence in the active centre of phosphoglucomutase | journal=Biochemical Journal | volume=79 | pages=456–469 | pmid=13771000 | pmc=1205670 | issue=3 }}.
*{{citation | last1=Marcker | first1=K. | last2=Sanger | first2=F. | year=1964 | title=''N''-formyl-methionyl-S-RNA | journal=Journal of Molecular Biology | volume=8 | pages=835–840 | pmid=14187409 | doi=10.1016/S0022-2836(64)80164-9 | issue=6 }}.
*{{citation | last1=Sanger | first1=F. | last2=Brownlee | first2=G.G. | last3=Barrell | first3=B.G. | year=1965 | title= A two-dimensional fractionation procedure for radioactive nucleotides | journal=Journal of Molecular Biology | volume=13 | issue=2 | pages=373–398 | pmid=5325727 | doi=10.1016/S0022-2836(65)80104-8 }}.
*{{citation | last1=Brownlee | first1=G.G.| last2=Sanger | first2=F. | last3=Barrell | first3=B.G. | year=1967 | title= Nucleotide sequence of 5S-ribosomal RNA from ''Escherichia coli'' | journal=Nature | volume=215 | issue=5102 | pages=735–736 | pmid=4862513 | doi=10.1038/215735a0 |bibcode = 1967Natur.215..735B }}.
*{{citation | last1=Brownlee | first1=G.G. | last2=Sanger | first2=F. | year=1967 | title= Nucleotide sequences from the low molecular weight ribosomal RNA of ''Escherichia coli'' | journal=Journal of Molecular Biology | volume=23 | issue=3 | pages=337–353 | pmid=4291728 | doi=10.1016/S0022-2836(67)80109-8 }}.
*{{citation | last1=Brownlee | first1=G.G.| last2=Sanger | first2=F. | last3=Barrell | first3=B.G. | year=1968 | title= The sequence of 5S ribosomal ribonucleic acid | journal=Journal of Molecular Biology | volume=34 | issue=3 | pages=379–412 | pmid=4938553 | doi=10.1016/0022-2836(68)90168-X }}.
*{{citation | last1=Adams | first1=J.M. | last2=Jeppesen | first2=P.G. | last3=Sanger | first3=F. | last4=Barrell | first4=B.G. | year=1969 | title= Nucleotide sequence from the coat protein cistron of R17 bacteriophage RNA | journal=Nature | volume=223 | issue=5210 | pages=1009–1014 | pmid=5811898 | doi=10.1038/2231009a0 |bibcode = 1969Natur.223.1009A }}.
*{{citation | last1=Barrell | first1=B.G. | last2=Sanger | first2=F. | year=1969 | title=The sequence of phenylalanine tRNA from ''E. coli'' | journal=FEBS Letters | volume=3 | issue=4 | pages=275–278 | pmid=11947028 | doi=10.1016/0014-5793(69)80157-2 }}.
*{{citation | last1=Jeppesen | first1=P.G. | last2=Barrell | first2=B.G. | last3=Sanger | first3=F. | last4=Coulson | first4=A.R. | year=1972 | title= Nucleotide sequences of two fragments from the coat-protein cistron of bacteriophage R17 ribonucleic acid | journal=Biochemical Journal | volume=128 | issue=5 | pages=993–1006 | pmid=4566195 | pmc=1173988 }}.
*{{citation | doi=10.1073/pnas.70.4.1209 | last1=Sanger | first1=F. | last2=Donelson | first2=J.E. | last3=Coulson | first3=A.R. | last4=Kössel | first4=H. | last5=Fischer | first5=D. | year=1973 | title= Use of DNA Polymerase I Primed by a Synthetic Oligonucleotide to Determine a Nucleotide Sequence in Phage f1 DNA | journal=Proceedings of the National Academy of Sciences USA | volume=70 | issue=4 | pages=1209–1213 | pmid=4577794 | pmc=433459 |bibcode = 1973PNAS...70.1209S }}.
*{{citation | last1=Sanger | first1=F. | last2=Coulson | first2=A.R. | year=1975 | title= A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase | journal=Journal of Molecular Biology | volume=94 | issue=3 | pages=441–448 | pmid=1100841 | doi=10.1016/0022-2836(75)90213-2 }}.
*{{citation | doi=10.1073/pnas.74.12.5463 | last1=Sanger| first1=F. | last2=Nicklen| first2=S. | last3=Coulson| first3=A.R.|title=DNA sequencing with chain-terminating inhibitors| journal=Proceedings of the National Academy of Sciences USA | year=1977 | volume=74 | issue=12 | pages=5463–5467 | pmid=271968 | pmc=431765 |bibcode = 1977PNAS...74.5463S }}. According to the Institute for Scientific Information (ISI) database, by October 2010 this paper had been cited over 64,000 times.
*{{citation | last1=Sanger | first1=F. | last2=Air | first2=G.M. | last3=Barrell | first3=B.G. | last4=Brown | first4=N.L. | last5=Coulson | first5=A.R. | last6=Fiddes | first6=C.A. | last7=Hutchinson | first7=C.A. | last8=Slocombe | first8=P.M. | last9=Smith | first9=M. | year=1977 | title= Nucleotide sequence of bacteriophage φX174 DNA | journal=Nature | volume=265 | issue=5596 | pages=687–695 | pmid=870828 | doi=10.1038/265687a0 |bibcode = 1977Natur.265..687S }}.
*{{citation | last1=Sanger | first1=F. | last2=Coulson | first2=A.R. | year=1978 | title= The use of thin acrylamide gels for DNA sequencing | journal= FEBS Letters | volume=87 | issue=1 | pages=107–110 | pmid=631324 | doi=10.1016/0014-5793(78)80145-8 }}.
*{{citation | last1=Sanger |first1=F. | last2=Coulson | first2=A.R. | last3=Barrell | first3=B.G. | last4=Smith | first4= A.J. | last5=Roe | first5=B.A. | year=1980 | title= Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing | journal=Journal of Molecular Biology | volume=143 | issue=2 | pages=161–178 | pmid=6260957 | doi=10.1016/0022-2836(80)90196-5 }}.
*{{citation | last1=Anderson | first1=S. | year=1981 | last2=Bankier | first2=A.T. | last3=Barrell | first3=B.G. | last4=De Bruijn | first4=M.H. | last5=Coulson | first5=A.R. | last6=Drouin | first6=J. | last7=Eperon | first7=I.C. | last8=Nierlich | first8=D.P. | last9=Roe | first9=B.A. | title= Sequence and organization of the human mitochondrial genome | journal=Nature | volume=290 | issue=5806 | pages=457–465 | pmid=7219534 | doi=10.1038/290457a0 |bibcode = 1981Natur.290..457A }}.
*{{citation | last1=Anderson | first1=S. | last2=De Bruijn | year=1982 | first2=M.H. | last3=Coulson | first3=A.R. | last4=Eperon | first4=I.C. | last5=Sanger | first5=F. | last6=Young | first6=I.G. | title= Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome | journal=Journal of Molecular Biology | volume=156 | issue=4 | pages=683–717 | pmid=7120390 | doi=10.1016/0022-2836(82)90137-1 }}.
*{{citation | last1=Sanger | first1=F. | last2=Coulson | first2=A.R. | last3=Hong | first3=G.F. | last4=Hill | first4=D.F. | last5=Petersen | first5=G.B. | year=1982 | title= Nucleotide sequence of bacteriophage λ DNA | journal=Journal of Molecular Biology | volume=162 | issue=4 | pages=729–773 | pmid=6221115 | doi=10.1016/0022-2836(82)90546-0 }}.
*{{citation | last=Sanger | first=F. | year=1988 | title=Sequences, sequences, and sequences | journal=Annual Review of Biochemistry | volume=57 | pages=1–28 | pmid=2460023 | doi=10.1146/annurev.bi.57.070188.000245 }}.
</div>



== Kaynakça ==

<references />

==Ek okumalar==
*{{citation| first=John | last=Finch | title=A Nobel Fellow on every floor: a history of the Medical Research Council Laboratory of Molecular Biology | publisher=Medical Research Council | place=Cambridge | year=2008 | isbn=978-1-84046-940-0}}.
*{{citation | last1=Sanger | first1=F. | last2= Dowding | first2=M. | year=1996 | title=Selected Papers of Frederick Sanger: with commentaries | publisher= World Scientific | place=Singapore | isbn= 981-02-2430-3 }}.

==Dış bağlantılar==
* [http://www.sanger.ac.uk/ The Sanger Institute]
* [http://nobelprize.org/nobel_prizes/chemistry/laureates/1958/ About the 1958 Nobel Prize]
* [http://nobelprize.org/nobel_prizes/chemistry/laureates/1980/ About the 1980 Nobel Prize]
* [http://www.vega.org.uk/series/facetoface/sanger/index.php Fred Sanger] 2001 Video Documentary by The Vega Science Trust
* [http://www.npg.org.uk/live/search/person.asp?search=ss&sText=Sanger&LinkID=mp06016 National Portrait Gallery]
* [http://www.alanmacfarlane.com/ancestors/sanger.htm Frederick Sanger interviewed by Alan Macfarlane, 24th August 2007 (film)]
* {{citation | title=Interviews with Nobel Prize winning scientists: Dr Frederick Sanger | url=http://www.bbc.co.uk/archive/scientists/10603.shtml | year=c. 1985 | publisher=British Broadcasting Corporation }}. Interviewed by [[Lewis Wolpert]]. Duration 1 hour.

Sayfanın 22.35, 9 Mart 2013 tarihindeki hâli

Frederick Sanger
Frederick Sanger
Doğum13 Ağustos 1918 (105 yaşında)
Gloucestershire, İngiltere, Birleşik Krallık
Vatandaşlık Birleşik Krallık
Mezun olduğu okul(lar)University of Cambridge
ÖdüllerNobel Kimya Ödülü (1958)
Nobel Kimya Ödülü (1980)
Kariyeri
DalıBiyokimya
Çalıştığı kurumlarUniversity of Cambridge
Laboratory of Molecular Biology
Doktora
danışmanı		Albert Neuberger
Doktora öğrencileriRodney Robert Porter
Liz Blackburn

Frederick Sanger (d. 13 Ağustos 1918) Britanyalı biyokimyager. 1958 ve 1980 yıllarında 2 kez Nobel Kimya Ödülü kazanmıştır ve bu ödülü 2 kez kazanan tek kişidir. 1958 yılında "proteinlerin, özellikle de insülinin yapısı üzerine çalışmaları için" Nobel Kimya Ödülü kazanmıştır. 1980 yılında da "nükleik asitlerdeki baz dizilerinin belirlenmesiyle ilgili katkıları nedeniyle" Walter Gilbert ile birlikte bu ödülü kazanmıştır. Aynı yıl ayrıca Paul Berg, "nükleik asitlerin, özellikle de rekombinant DNA'nın biyokimyası üzerine temel çalışmaları için" Nobel Kimya Ödülü'nü kazanan diğer isim olmuştur.[1]

Sanger iki Nobel Ödülü'ne layık görülen dört kişiden birisidir.

Seçilmiş yayınları

  • Sanger, F.; Tuppy, H. (1951a), "The amino-acid sequence in the phenylalanyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates", Biochemical Journal, 49 (4), ss. 463–481, PMC 1197535 $2, PMID 14886310 .
  • Sanger, F.; Tuppy, H. (1951b), "The amino-acid sequence in the phenylalanyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates", Biochemical Journal, 49 (4), ss. 481–490, PMC 1197536 $2, PMID 14886311 .
  • Sanger, F.; Thompson, E.O.P. (1953a), "The amino-acid sequence in the glycyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates", Biochemical Journal, 53 (3), ss. 353–366, PMC 1198157 $2, PMID 13032078 .
  • Sanger, F.; Thompson, E.O.P. (1953b), "The amino-acid sequence in the glycyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates", Biochemical Journal, 53 (3), ss. 366–374, PMC 1198158 $2, PMID 13032079 .
  • Sanger, F.; Thompson, E.O.p.; Kitai, R. (1955), "The amide groups of insulin", Biochemical Journal, 59 (3), ss. 509–518, PMC 1216278 $2, PMID 14363129 .
  • Ryle, A.P.; Sanger, F.; Smith, L.F.; Kitai, R. (1955), "The disulphide bonds of insulin", Biochemical Journal, 60 (4), ss. 541–556, PMC 1216151 $2, PMID 13249947 .
  • Brown, H.; Sanger, F.; Kitai, R. (1955), "The structure of pig and sheep insulins", Biochemical Journal, 60 (4), ss. 556–565, PMC 1216152 $2, PMID 13249948 .
  • Sanger, F. (1959), "Chemistry of Insulin: determination of the structure of insulin opens the way to greater understanding of life processes", Science, 129 (3359), ss. 1340–1344, Bibcode:1959Sci...129.1340G, doi:10.1126/science.129.3359.1340, PMID 13658959 .
  • Milstein, C.; Sanger, F. (1961), "An amino acid sequence in the active centre of phosphoglucomutase", Biochemical Journal, 79 (3), ss. 456–469, PMC 1205670 $2, PMID 13771000 .
  • Marcker, K.; Sanger, F. (1964), "N-formyl-methionyl-S-RNA", Journal of Molecular Biology, 8 (6), ss. 835–840, doi:10.1016/S0022-2836(64)80164-9, PMID 14187409 .
  • Sanger, F.; Brownlee, G.G.; Barrell, B.G. (1965), "A two-dimensional fractionation procedure for radioactive nucleotides", Journal of Molecular Biology, 13 (2), ss. 373–398, doi:10.1016/S0022-2836(65)80104-8, PMID 5325727 .
  • Brownlee, G.G.; Sanger, F.; Barrell, B.G. (1967), "Nucleotide sequence of 5S-ribosomal RNA from Escherichia coli", Nature, 215 (5102), ss. 735–736, Bibcode:1967Natur.215..735B, doi:10.1038/215735a0, PMID 4862513 .
  • Brownlee, G.G.; Sanger, F. (1967), "Nucleotide sequences from the low molecular weight ribosomal RNA of Escherichia coli", Journal of Molecular Biology, 23 (3), ss. 337–353, doi:10.1016/S0022-2836(67)80109-8, PMID 4291728 .
  • Brownlee, G.G.; Sanger, F.; Barrell, B.G. (1968), "The sequence of 5S ribosomal ribonucleic acid", Journal of Molecular Biology, 34 (3), ss. 379–412, doi:10.1016/0022-2836(68)90168-X, PMID 4938553 .
  • Adams, J.M.; Jeppesen, P.G.; Sanger, F.; Barrell, B.G. (1969), "Nucleotide sequence from the coat protein cistron of R17 bacteriophage RNA", Nature, 223 (5210), ss. 1009–1014, Bibcode:1969Natur.223.1009A, doi:10.1038/2231009a0, PMID 5811898 .
  • Barrell, B.G.; Sanger, F. (1969), "The sequence of phenylalanine tRNA from E. coli", FEBS Letters, 3 (4), ss. 275–278, doi:10.1016/0014-5793(69)80157-2, PMID 11947028 .
  • Jeppesen, P.G.; Barrell, B.G.; Sanger, F.; Coulson, A.R. (1972), "Nucleotide sequences of two fragments from the coat-protein cistron of bacteriophage R17 ribonucleic acid", Biochemical Journal, 128 (5), ss. 993–1006, PMC 1173988 $2, PMID 4566195 .
  • Sanger, F.; Donelson, J.E.; Coulson, A.R.; Kössel, H.; Fischer, D. (1973), "Use of DNA Polymerase I Primed by a Synthetic Oligonucleotide to Determine a Nucleotide Sequence in Phage f1 DNA", Proceedings of the National Academy of Sciences USA, 70 (4), ss. 1209–1213, Bibcode:1973PNAS...70.1209S, doi:10.1073/pnas.70.4.1209, PMC 433459 $2, PMID 4577794 .
  • Sanger, F.; Coulson, A.R. (1975), "A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase", Journal of Molecular Biology, 94 (3), ss. 441–448, doi:10.1016/0022-2836(75)90213-2, PMID 1100841 .
  • Sanger, F.; Nicklen, S.; Coulson, A.R. (1977), "DNA sequencing with chain-terminating inhibitors", Proceedings of the National Academy of Sciences USA, 74 (12), ss. 5463–5467, Bibcode:1977PNAS...74.5463S, doi:10.1073/pnas.74.12.5463, PMC 431765 $2, PMID 271968 . According to the Institute for Scientific Information (ISI) database, by October 2010 this paper had been cited over 64,000 times.
  • Sanger, F.; Air, G.M.; Barrell, B.G.; Brown, N.L.; Coulson, A.R.; Fiddes, C.A.; Hutchinson, C.A.; Slocombe, P.M.; Smith, M. (1977), "Nucleotide sequence of bacteriophage φX174 DNA", Nature, 265 (5596), ss. 687–695, Bibcode:1977Natur.265..687S, doi:10.1038/265687a0, PMID 870828 .
  • Sanger, F.; Coulson, A.R. (1978), "The use of thin acrylamide gels for DNA sequencing", FEBS Letters, 87 (1), ss. 107–110, doi:10.1016/0014-5793(78)80145-8, PMID 631324 .
  • Sanger, F.; Coulson, A.R.; Barrell, B.G.; Smith, A.J.; Roe, B.A. (1980), "Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing", Journal of Molecular Biology, 143 (2), ss. 161–178, doi:10.1016/0022-2836(80)90196-5, PMID 6260957 .
  • Anderson, S.; Bankier, A.T.; Barrell, B.G.; De Bruijn, M.H.; Coulson, A.R.; Drouin, J.; Eperon, I.C.; Nierlich, D.P.; Roe, B.A. (1981), "Sequence and organization of the human mitochondrial genome", Nature, 290 (5806), ss. 457–465, Bibcode:1981Natur.290..457A, doi:10.1038/290457a0, PMID 7219534 .
  • Anderson, S.; De Bruijn, M.H.; Coulson, A.R.; Eperon, I.C.; Sanger, F.; Young, I.G. (1982), "Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome", Journal of Molecular Biology, 156 (4), ss. 683–717, doi:10.1016/0022-2836(82)90137-1, PMID 7120390 .
  • Sanger, F.; Coulson, A.R.; Hong, G.F.; Hill, D.F.; Petersen, G.B. (1982), "Nucleotide sequence of bacteriophage λ DNA", Journal of Molecular Biology, 162 (4), ss. 729–773, doi:10.1016/0022-2836(82)90546-0, PMID 6221115 .
  • Sanger, F. (1988), "Sequences, sequences, and sequences", Annual Review of Biochemistry, 57, ss. 1–28, doi:10.1146/annurev.bi.57.070188.000245, PMID 2460023 .


Kaynakça

  1. ^ http://www.britannica.com/EBchecked/topic/522340/Frederick-Sanger

Ek okumalar

  • Finch, John (2008), A Nobel Fellow on every floor: a history of the Medical Research Council Laboratory of Molecular Biology, Cambridge: Medical Research Council, ISBN 978-1-84046-940-0 .
  • Sanger, F.; Dowding, M. (1996), Selected Papers of Frederick Sanger: with commentaries, Singapore: World Scientific, ISBN 981-02-2430-3 .

Dış bağlantılar

"https://tr.wikipedia.org/w/index.php?title=Frederick_Sanger&oldid=12926944" sayfasından alınmıştır